In 1972 Zeta Phi Beta Sorority and the March of Dimes began a collaborative program called the Stork's Nest. This program has both a service and educational components. The service is the establishment of a distribution site, the "Nest," where expectant mothers referred by cooperating hospitals, clinics, and health centers can get necessary items such as layettes and strollers and baby furniture at minimal or no costs. The educational component consist of seven sessions covering prenatal care, nutrition, drugs, alcohol, smoking, genetics, infant care and parenting.

Sigma Nu Zeta chapter is proud to have sponsored the Sorority's national program, The Stork's Nest at the North General Hospital in Harlem from 2006 to 2007. Currently the Stork's Nest Program sponsored by the chapter, is being restructured to target women in the Harlem community in satellite locations.

In 2006 Zeta Phi Beta Sorority, Inc.,  a national team for the March of Dimes' signature WalkAmerica project for the 3rd year in a row, was the #1 WalkAmerica team in the Adult clubs and Organizations category raising over $200,000. Locally, Sigma Nu Zeta Chapter was #1 for monies raised for March of Dimes in Zeta Phi Beta Sorority, Inc. - New York State.

In 2007, Sigma Nu Zeta Chapter raised more than $9,000 which positioned the chapter in the number one spot on the national level  for monies raised for WalkAmerica by Zeta Phi Beta Sorority, Inc.

In 2008, Sigma Nu Zeta chapter sponsored its first dedicated fundraising event for the March of Dimes at the New York State office building in Harlem, NY. Moving forward the chapter hopes to continue to strengthen its ties with the local and national March of Dimes office.